TY - JOUR A2 - Keating, Armand AU - Chen, Jinyun AU - Wang, Qian AU - Feng, Xuebing AU - Zhang, Zhuoya AU - Geng, Linyu AU - Xu, Ting AU - Wang, Dandan AU - Sun, Lingyun PY - 2016 DA - 2016/12/07 TI - Umbilical Cord-Derived Mesenchymal Stem Cells Suppress Autophagy of T Cells in Patients with Systemic Lupus Erythematosus via Transfer of Mitochondria SP - 4062789 VL - 2016 AB - Aberrant autophagy played an important role in the pathogenesis of autoimmune diseases, especially in systemic lupus erythematosus (SLE).在这次研究中,我们显示SLE病人的T细胞自发性比健康控件高激活T单元中观察到自片活动与吸附率相关此外,自发拉皮素激活会增加T细胞吸附症,而自发3MA抑制会减少T细胞吸附症UP-MSCs可抑制活性T单元的二分位生物生成以下调自发并进而通过二分位转换减少T单位单片分解并从而在SLE处理中发挥重要作用SN-1687-966XUR-https://doi.org/101155/2016/4062789DO-10.1155+16/4062789JF-Stemells国际PB-Hindawi出版公司KW-ER-