TY - JOUR A2 - 巴索，库尔特AU - 森，F AU - Barni，S. AU - Cianferoni，A. AU - 普奇，N. AU - 德·马蒂诺，M. AU - 十一月四日，E. PY - 2009 DA -2009/11/17 TI - 细胞因子表达的CD3 +细胞与食物蛋白质诱导的小肠结肠炎综合征（FPIES）的婴儿：病例报告SP - 679381 VL - 2009年AB - 食品蛋白诱导肠炎综合征（FPIES）是一种非特异性IgE介导的食物过敏特点是剧烈的呕吐，腹泻，常失败的婴儿茁壮成长。触发食源性蛋白是从再曝光的因果蛋白后几个小时内饮食和RECUR删除后症状通常解决。诊断根据临床症状和阳性食物挑战。在这项研究中，我们报道了在8个月大的男婴FPIES的水稻情况。我们进行了双盲安慰剂对照食物激发（DBPCFC）对水稻和我们测量白介素-4的胞内T细胞表达（IL-4）;IL-10和干扰素 γ （IFN-γ γ ）前和期间急性攻击后FPIES反应和耐受性水稻已经达到时。首次，我们描述在IFN-T细胞IL-4和下降的增加 γ expression after a positive challenge with rice (i.e. rice triggered a FPIES attack) and an increase in T cell IL-10 expression after rice challenge 6 months later after a negative challenge (i.e., the child had acquired tolerance to rice) in an 8 month old with documented FPIES to rice. A Th2 activation associated with high IL-4 levels may contribute to the pathophysiology of the disease. On the other hand, T cell-derived IL-10 may play a role in the acquisition of immunotolerance by regulating the Th1 and Th2 responses. SN - 2314-8861 UR - https://doi.org/10.1155/2009/679381 DO - 10.1155/2009/679381 JF - Clinical and Developmental Immunology PB - Hindawi Publishing Corporation KW - ER -