TY - JOUR A2 - Santos, Adalberto R. AU - Rutanga, Jean Pierre AU - Nyirahabimana, Therese PY - 2016 DA - 2016/11/16 TI -细菌血流感染的分子诊断工具的临床意义:SP - 6412085 VL - 2016 AB -细菌血流感染(bBSI)是指由细菌引起的任何形式的血液循环系统侵袭，在危重患者中可导致死亡。因此，有必要对败血症患者进行快速、准确的诊断和治疗。到目前为止，已经开发出了不同的分子诊断工具。大多数这些工具集中放大的基础技术,如聚合酶链反应(PCR),允许检测核酸(DNA和小分子rna)的细菌种类和测序或核酸杂交,使细菌的检测,以减少延迟的适当的抗生素therapy. However, there is still a need to improve sensitivity of most molecular techniques to enhance their accuracy and allow exact and on time antibiotic therapy treatment. In this regard, we conducted a systematic review of the existing studies conducted in molecular diagnosis of bBSIs, with the main aim of reporting on clinical significance and benefits of molecular diagnosis to patients. We searched both Google Scholar and PubMed. In total, eighteen reviewed papers indicate that shift from conventional diagnostic methods to molecular tools is needed and would lead to accurate diagnosis and treatment of bBSI. SN - 1687-708X UR - https://doi.org/10.1155/2016/6412085 DO - 10.1155/2016/6412085 JF - Interdisciplinary Perspectives on Infectious Diseases PB - Hindawi Publishing Corporation KW - ER -