TY - JOUR A2 - Selvaggi, Francesco AU - Cai, Ou AU - Huang, Zhenpeng AU - Li, Ming AU - Zhang, Chaoqun AU - Xi, Fengbo AU - Tan, Shiyun PY - 2018 DA - 2018/01/21 TI - Association betweenHelicobacter pyloriInfection and Nonalcoholic Fatty Liver Disease: A Single-Center Clinical Study SP - 8040262 VL - 2018 AB - Objective. To investigate the association between Helicobacter pylori( H. pylori) infection and nonalcoholic fatty liver disease (NAFLD). Methods. Data from 2051 participants who underwent¹³C尿素呼气试验和腹部超声波examinations was collected. Participants were allocated to NAFLD risk group and NAFLD nonrisk group based on definite risk factors for NAFLD. The relationship between H. pyloriinfection and NAFLD was analyzed. Results. No significant difference was found between rates of H. pyloriinfection and NAFLD using the chi-square test ( P = 0.30 ) or regression analysis ( P = 0.70 ). There was no significant difference between rates of H. pyloriinfection with and without NAFLD ( P = 0.47 ) in the NAFLD risk group or in the NAFLD nonrisk group ( P = 0.59 ). There was no significant difference between rates of H. pyloriinfection in men ( P = 0.69 ) and in women ( P = 0.27 ) or in participants aged 18–40 years ( P = 0.43 ), 41–65 years ( P = 0.14 ), and ≥66 years ( P = 0.66 ) with and without NAFLD in the NAFLD risk group or between the same sex or age groups ( P = 0.82 , P = 0.66 , P = 0.24 , P = 0.53 , and P = 1.00 , resp.) in the NAFLD nonrisk group. Conclusions. H. pyloriinfection does not appear to increase the NAFLD prevalence rate or to be associated with, or a risk factor for, NAFLD. SN - 1687-6121 UR - https://doi.org/10.1155/2018/8040262 DO - 10.1155/2018/8040262 JF - Gastroenterology Research and Practice PB - Hindawi KW - ER -