TY -的A2 -钱德拉,哈瑞盟助飞,乔纳森•AU -兹•伊曼纽尔AU - Duah Boakye,偏航AU - Oppong Bekoe,艾美莉亚AU - Oppong Bekoe,塞缪尔盟——Asare-Nkansah塞缪尔盟——Spiegler Verena盟——Hensel Andreas AU - Liebau,伊娃盟——Agyare基督教PY - 2022 DA - 2022/12/31 TI -驱虫剂代理从非洲药用植物:审查和前景SP - 8023866六世- 2022 AB -土壤传播的蠕虫病影响了全球超过15亿人,在很大程度上仍然是一个在非洲的卫生问题。这些感染贫穷国家的一个巨大的经济负担和影响畜牧业生产,造成重大的经济损失和可怜的动物健康。打虫药耐药性的出现,尤其是在牲畜,以及潜在的广泛的人类创建一个需要发展的替代疗法。药用植物的管理扮演了一个重要的角色在人类和家畜寄生虫病,特别是在非洲。这份报告评论打虫药的研究一直在进行药用植物种植在非洲和发表在过去的二十年。各电子数据库,搜索了,只有完整的英文文章被包括在审查中。报告显示,水和hydroalcoholic提取物和极地分数获得这些原油提取形成的主要(80%)形式提取进行了研究。药用植物提取物,研究了化合物与不同的化学集团的打虫药的潜力。多酚类和萜类化合物是最报告组。64%以上的研究工作在体外实验中对寄生和nonparasitic线虫模型。 Egg hatch inhibition, larval migration inhibition, and paralysis are the common parameters assessed in vitro. About 72% of in vivo models involved small ruminants, 15% rodents, and 5% chicken. Egg and worm burden are the main factors assessed in vivo. There were no reports on interventions in humans cited within the period under consideration. Also, few reports have investigated the potential of combining plant extracts with common anthelmintic drugs. This review reveals the huge potential of African medicinal plants as sources of anthelmintic agents and the dire need for in-depth clinical studies of extracts, fractions, and compounds from African plants as anthelmintic agents in livestock, companion animals, and humans. SN - 1741-427X UR - https://doi.org/10.1155/2022/8023866 DO - 10.1155/2022/8023866 JF - Evidence-Based Complementary and Alternative Medicine PB - Hindawi KW - ER -