TY -的A2 Kuwabara宽子非盟- Dabrowski杜米尼克盟——Ozluk郑伊健AU -巴尔贝托,西尔维亚AU -魏,埃里克·x PY - 2020 DA - 2020/10/16 TI -局灶节段性肾小球硬化症前2型乳头状肾细胞癌SP - 8811905六世- 2020 AB -肾细胞癌(RCC)是主要的成人肾恶性肿瘤。的四个亚型,乳头状肾细胞癌(P-RCC)是第二个最常见的和可以细分为I型,II型和I型和II的混合物。局灶性节段性肾小球硬化症(FSGS)是最常见的所有年龄段的glomerulopathy,它可以被视为一个副肿瘤综合征。碾压混凝土,一般来说,众所周知,现在有许多多种症状,并在这些glomerulopathies。很少,碾压混凝土和glomerulopathies可能重叠在同一个病人。在这里,我们报告一位58岁男性的过去病史FSGS和慢性肾脏疾病(CKD),第三阶段,他发现有一个附带肾质量,后来被诊断为II型P-RCC。组织学显示pseudostratified肿瘤细胞与嗜酸性胞浆的形成乳头状配置和显示领域的坏死。前FSGS诊断展出节段性硬化,耐火塔夫茨,毛细管膜起皱。间隔一段时间1.5年glomerulopathy和恶性肿瘤的诊断。肿瘤被发现在TIb的阶段。 To our knowledge, this may be the first reported case of usual-type FSGS as paraneoplastic glomerulopathy (PG) preceding P-RCC. Because FSGS only sparingly affects the kidney and is a common glomerulopathy in adults, it is reasonable to complete comprehensive diagnostic studies and commence medically necessary treatment, especially in the background of other renal comorbidities. These preexisting comorbidities may be associated with malignancy very early in its course. The probability of RCC-associated paraneoplastic glomerulopathy is low, which means an already incidentally found renal mass may conceal a serpentine paraneoplastic syndrome. A more developed understanding of these manifestations can lead experienced clinicians to suspect and possibly uncover an insidious RCC before it advances. SN - 2090-6781 UR - https://doi.org/10.1155/2020/8811905 DO - 10.1155/2020/8811905 JF - Case Reports in Pathology PB - Hindawi KW - ER -