TY -的A2 -塔林,乔凡尼非盟-南帝,Minesh盟——阿尼尔,拉胡尔盟——Hamaty爱德华AU -亚当斯,威廉盟——Stidd大卫AU -加尔达Krizelle盟——Kandukuri哈里PY - 2020 DA - 2020/01/04 TI -一种罕见的颅内Nongerminomatous生殖细胞肿瘤在21岁的罗马尼亚男性SP - 3787250六世- 2020 AB - Extragonadal生殖细胞肿瘤是一种罕见的实体,在婴幼儿更为普遍,中线结构与偏好。颅内生殖细胞肿瘤的类别分为纯生殖细胞肿瘤(生殖)与nongerminomatous生殖细胞肿瘤(NGGCTs)。他们通常出现在第二个十年的生活与男性占优势。我们报告一例少见的颅内NGGCT在21岁的罗马尼亚男,面对投诉的呕吐,共济失调步态和复视。电脑断层扫描头的急诊室发现松果体/ suprapineal质量以及阻塞性脑积水和扩张侧和第三脑室出血。MRI的颈、胸、腰椎显示没有证据表明leptomeningeal转移。病人血清标志物升高beta-hCG和法新社,指向nongerm细胞瘤的诊断,如纯生殖芽细胞肿瘤,这些标记是正常的。从质量效应,缓解梗阻病人有内镜第三脑室切开术(EVT)。然而,手术后,他发达中央尿崩症并发症与三相的反应。切片的质量显示非典型细胞与粒状结构和非典型腺体正面免疫组织学NGGCT标记。 These findings supported the diagnosis of mixed germ cell tumor with yolk sac carcinoma and seminoma components. Patient’s transient central diabetes resolved with normalization in his urine output. He was eventually stabilized and returned to Romania for further management. In summary, intracranial germ cell tumors are rare brain tumors that should be distinguished based on histology and tumor markers as they will help in the guidance of therapy. An initial evaluation with neuroimaging, tumor markers, cytology from CSF, and biopsy is a must to distinguish further treatment and prognosis. SN - 2090-6706 UR - https://doi.org/10.1155/2020/3787250 DO - 10.1155/2020/3787250 JF - Case Reports in Oncological Medicine PB - Hindawi KW - ER -