TY -的A2 Palmirotta拉斐尔盟,佐藤Kunitomo盟,田中Toshihide盟——加藤Naoki盟——Ishii Takuya盟——Terao Toru AU - Murayama,祐一PY - 2014 DA - 2014/12/28 TI -转移性小脑胃肠道间质肿瘤引起的阻塞性脑积水小肠:SP - 343178 VL - 2014 AB -胃肠道间质瘤(GIST)是一种c-kit阳性的胃肠道、肠系膜或大网膜间质瘤，极少转移到大脑。转移到小脑是特别罕见的。一名80岁男性，表现为恶心、呕吐及意识障碍。磁共振成像(MRI)显示肿瘤在小脑蚓部引起阻塞性脑积水。病人随后接受正中线枕骨下开颅术，肿瘤被完全切除。免疫组化分析显示肿瘤细胞c-kit和CD34阳性，诊断GIST有小脑转移。术后给予放射治疗。经手术及放射治疗后，患者因小肠肿瘤引起肠梗阻，行剖腹手术切除肿瘤。腹部手术后，出现左侧偏瘫和意识障碍。 Computed tomography showed recurrent large tumor with perifocal edema in the right frontal lobe of the brain. The patient died 3 months after initial craniotomy. Intracranial metastasis of GIST is extremely rare. In cases such as the present, where the condition of the patient rapidly deteriorates and features such as rising intracranial pressure and ileus prevent the use of oral agents, molecular-targeted agents administered by intravenous infusion should be utilized. SN - 2090-6706 UR - https://doi.org/10.1155/2014/343178 DO - 10.1155/2014/343178 JF - Case Reports in Oncological Medicine PB - Hindawi Publishing Corporation KW - ER -