TY - JOUR A2 - Guimarães, Hercília AU - Gupta, Samir AU - Donn, Steven M. PY - 2012 DA - 2012/12/03 TI - Novel Approaches to Surfactant Administration SP - 278483 VL - 2012 AB - Surfactant replacement therapy has been the mainstay of treatment for preterm infants with respiratory distress syndrome for more than twenty years. For the most part, surfactant is administered intratracheally, followed by mechanical ventilation. In recent years, the growing interest in noninvasive ventilation has led to novel approaches of administration. This paper will review these techniques and the associated clinical evidence. SN - 2090-1305 UR - https://doi.org/10.1155/2012/278483 DO - 10.1155/2012/278483 JF - Critical Care Research and Practice PB - Hindawi Publishing Corporation KW - ER -