TY - JOUR A2 - 盖伦·涅托，赫拉尔E. AU - Kusumawati，维迪娅AU - 刻满，Kusnarman AU - 苏哈托，Setyawati PY - 2016 DA - 2016年2月18日TI - 抑制性的影响石榴6028989 VL - - 2016 AB - 这项研究旨在评估是否对血管紧张素II I型受体及血栓从先兆子痫患者SP等离子诱导内皮细胞B2果提取物 石榴果实提取物调制血管紧张素II类型I受体（AT1-R）和血栓素B2水平在从先兆子痫患者诱导血浆内皮细胞。从人脐静脉内皮细胞获得的内皮细胞。在汇合时，内皮细胞分为5组，其中包括暴露于来自正常妊娠（NP）2％血浆内皮细胞，血管内皮细胞暴露于来自在存在暴露于PP先兆子痫患者（PP），和内皮细胞2％血浆的乙醇提取物 石榴（PP + PG）在以下三种剂量：14;28;and 56 ppm. The expression of AT1-R was observed by immunohistochemistry technique, and thromboxane B2 level was done by immunoassay technique. Plasma from PP significantly increased AT1-R expression and thromboxane B2 levels compared to cells treated by normal pregnancy plasma. The increasing of AT1-R expression significantly ( P < 0.05 ）通过的高剂量治疗衰减 石榴提取。此外，血栓素B2水平的显著增加（ P < 0.05 ）通过的最低剂量治疗衰减 石榴提取。我们进一步认为， 石榴fruit protects and inhibits the sensitivity of endothelial cells to plasma from preeclamptic patients due to inhibition of AT1-R expression (56 ppm) and reduced thromboxane B2 levels (14 ppm). SN - 2090-3480 UR - https://doi.org/10.1155/2016/6028989 DO - 10.1155/2016/6028989 JF - Advances in Preventive Medicine PB - Hindawi Publishing Corporation KW - ER -